A member asked:

I was just told that my bone marrow biopsy showed i have a 3rd set of chromosome 8. i have none of the clinical features. is it possible the test is ?

5 doctors weighed in across 2 answers
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Trisomy 8 in marrow: This abnormality is not associated with any specific disease, since patients can have different clinical features, such as leukemia, polycythemia vera, and several other blood disorders. It's been suggested that the trisomy may be a secondary rather than primary event in the development of the disease. It's different than trisomy 8 as a primary genetic event-w/ fetal development problem etc.

Answered 2/2/2013

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Be more specific: Trisomy 8 may be acquired, rather than hereditary (from birth). Why was the bone marrow done? What underlying problem is there? This might explain the trisomy 8.

Answered 10/3/2016

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