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A 58-year-old female asked:

I had a bone marrow biopsy done a few days ago and the results just appeared on my health record. is this bad? abnormal plasma cells present (plasma cells show a mild lambda predominance, and aberrant coexpression of cd56?

2 doctor answers2 doctors weighed in
Dr. Donald Colantino
Internal Medicine 62 years experience
Multiple myeloma or AL amyloidosis come to mind. Presence of anemia,high serum calcium,bone pain are characteristics of myeloma. Both plasma cell dyscrasias can cause kidney damage & have elevated serum lambda or kappa light chains. A hematologist oncologist is best to evaluate & advise you. A serum& urine immunofixation,24 hour urine total protein are often key. Congo red stain shows amyloid
Dr. Gurmukh Singh
Pathology 50 years experience
All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, the information you provided is insufficient to provide any meaningful opinion. Wish you good health!
Last updated Feb 5, 2022

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