A member asked:

What does the brca in brca1 stand for?

13 doctors weighed in across 5 answers
Dr. Michael Zadeh answered

Specializes in General Surgery

The brca in brca1 and brca2 stands for breast cancer susceptibility gene. They are a type of gene known as tumor suppressor genes.

Answered Jul 29, 2015


Dr. Matt Malkin answered

Specializes in Anesthesiology

Breast cancer is my guess. Genetic researchers can actually come up with some crazy names and abbreviations. The fruitfly researchers i know tend to be even wackier. Fortunately, these researchers chose something straightforward and memorable, which helps spread the word of such a serious disease.

Answered Jul 20, 2012


Dr. Devon Webster answered

Specializes in Medical Oncology

Brca is short for breast cancer. That's because mutations in these genes increase the risk for breast cancer. The mutations also increase the risk for other cancers, but the higher rate of breast cancer was identified first, so that's how the genes were named.

Answered Jan 16, 2014


Dr. Judy Mouchawar answered

Specializes in Preventive Medicine

"BR" stands for breast "CA" stands for cancer In the mid-1990's, after years of research, two genes were found that are changed in many families with breast cancer. The first gene was named BRCA1 and the second gene was named BRCA2.

Answered May 12, 2015


Dr. Brian Nguyen answered

Specializes in Obstetrics and Gynecology

Women w/ 2+ immediate family members w/ a hx of breast/ovarian CA at 50% chance of developing breast cancer. If you have it, get screened with CA-125 blood test, ultrasound, mammogram/MRI, usually starting at age 30. Surgery after childbearing.

Answered Jun 7, 2019



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