A 22-year-old member asked:
About the brca-1 gene (breast cancer gene)...if a male is a carrier for the gene what will happen to his daughters?
3 doctor answers • 13 doctors weighed in
General Surgery 34 years experience
6.2k viewsReviewed >2 years ago
Medical Oncology 22 years experience
50% chance : Each child of a father carrying a brca mutation has a 50% chance of having the same mutated gene. If a daughter has the brca1 mutation, she will have a higher chance of developing breast and ovarian cancer at an early age. Any child of a parent with a brca mutation should have genetic counseling and testing before childbearing age.
6.1k viewsReviewed >2 years ago
Medical Oncology 35 years experience
50%: Each child of a brca mutation carrier has a 50/50 chance of getting the mutation regardless of gender. We usually test them for only that particular mutation (single site analysis) which is cheaper. Word of warning: two individuals with two different mutations can be married and then each child can inherit none, one, or both. We need to know the family history of both sides of the family.
5k viewsReviewed >2 years ago
Last updated Sep 28, 2016
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.