A 45-year-old member asked:
Which drug is best to stop clozapine and to reduce the withdrawal cholinergic rebound?
1 doctor answer • 2 doctors weighed in
Dr. Imad Khreimanswered
Psychiatry 39 years experience
See ur Doctor: stopping Clozapine is a Major decision in any treatment plan, it is taken very seriously by the treating physician and all risks and benefits are weighed carefully , it cant be done over the net, you have to see your prescribing physician and discuss with him the issue. good luck and feel better
3.4k viewsReviewed >2 years ago
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A 32-year-old member asked:
Do you know which drug is best to stop clozapine, and to reduce withdrawal cholinergic rebound?
2 doctor answers • 2 doctors weighed in
Dr. Erik Messamoreanswered
Psychiatry 24 years experience
Requires expert care: Withdrawing from clozapine may come with *many* potential consequences. I hope you have someone with sufficient expertise to help with the process.
The anticholinergic withdrawal syndrome (AWS) is often described as flu-like malaise. Brain-permable anticholinergic meds like benztropine (Cogentin) or scopolamine would be reasonable treatments for AWS.
This should be undertaken w a psychiatrist.
3k viewsReviewed Jan 10, 2021
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Last updated May 7, 2016
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