A member asked:

My doctor took me off clozapine cold turkey. he said he won't prescribe that if the fluoxetine works well. what am i to expect regarding withdrawal?

3 doctors weighed in across 2 answers
Dr. James Burns answered

Specializes in Emergency Medicine

Variable: The answer depends on how much you were taking and how long you were taking it. Typically, a temporary episode of mild agitation and possibly insomnia will occur but dissipate within 2-4 weeks. You may experience nothing. However, it is best not to take if not absolutely necessary. Don't believe your doctor would have stopped it if he/she thought it would seriously harm you.

Answered 5/15/2015

4.8k views

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Clozapine: Agree with earlier response that problems can be related to dose and duration of medication. Rapid discontinuation off of high doses can cause withdrawal symptoms such as headache, agitation, dizziness, nausea, vomiting, orthostatic hypotension, return of mania or rebound psychosis, or serotonin syndrome. I am assuming you were on low dose and might not have any adverse effects.

Answered 1/10/2021

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