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A member asked:
Had my ana tested 3 times, first time 1:640homogenous, second 1:180 speckled. now it is 1:640speckled and 1:180env pattern. pain & fatigue daily. ?
A doctor has provided 1 answer
ANA patterns: ANA is antibodies to cell nucleus.Normally we do not make antibodies to self. > 1;160 is found in autoimmune/connective tissue disease like lupus /scleroderma. Patterns differ with disease. Lupus is homogenous/speckled, whereas scleroderma can be speckled and nucleolar ( env). More testing like antiSmith/topoisomerase is needed. Correlate with symptoms. Follow with Rheumatologist.
Answered 10/31/2014
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