Nmr lipoprofiling, should this be used to better risk stratify?

So they tell me: "When LDL-C and LDL-P levels are discordant, risk of cardiovascular events has been proven to track with LDL-P more closely than LDL-C" my bias is to agree. the P means how many little LDL's there are while the LDL-C is an estimate based on the cholesterol. The dietary intake increases that value BUT doesn't predict risk well at all!

Use for Management: LDL can be estimated by cholesterol (LDL-C) or measured by NMR LDL particle number (LDL-P). When LDL-C and LDL-P disagree, CHD risk tracks with LDL-P, not LDL-C. Many expert panels advocate LDL-P to judge response and adjust therapy. Clinical utilization data confirms a significant reduction of CVD risk and events among high risk patients attaining low NMR LDL-P versus those managed to low LDL-C.

Absolutely superior!: Research identifying LDL particles as dominant factor driving atherosclerosis first published 1950. NIH.gov promoted cholesterol (made by every animal cell) as surrogate marker (knowing it was wrong issue) early 1970s for ↓ed cost for masses. A single LDL particle typically carries 3,000-6,000 fat molecules; how many are cholesterol varies widely (by 6:1 or more), thus LDL-C is a poor surrogate.