I'm supposed to take xifaxan (rifaximin) 3x a day. what time should i take each dose to space it out? should i wake up in the middle of the night to take a dose?

No: No, you do not have to take it at regular intervals, around breakfast, lunch and dinner will suffice. 6:00, 14:00, 22:00 will work, too, and that will be at regular intervals without getting up in the middle of the night.

Xifaxin: This drug is hardly absorbed into the system at all. I do not think you need to wake up in the middle of the night to take. It can be take with or without food. I think a good schedule would be breakfast, lunch and dinner.

TID =/ q8o: Taking a medication three times daily isn't same as taking it every 8hrs. Instead, it usually means only while awake then sleeping through night. Unasked question: what about four times daily vs every 6hrs? Again, it's more frequent than every 6hrs b/c it refers to four times while awake then sleeping through night. Theoretically, taking every 6hrs means you'd only get 6hrs rest before taking next