Neurosyphilis: This conditions may take many different forms, from meningovascular, tabes dorsalis, and so on. The generally approved regimen is penicillin G procaine, in a dosage of 2.4 million units administered intramuscularly once daily, plus probenecid, in a dosage of 500 mg orally four times daily, with both drugs given for 10 to 14 days. This should be followed by spinal tap to measure the serologic level
Answered 9/28/2016
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Treatment: Treatment Options for Neurosyphilis The antibiotic penicillin is used to treat syphilis and neurosyphilis. It may be injected or taken orally. The usual regimen lasts 10 to 14 days. The antibiotics probenecid and ceftriaxone are often used in conjunction with penicillin. Depending on your case, you may need to stay in the hospital while being treated. During your recovery, you will need blood tests at the three- and six-month marks. After that, you should have blood tests every year following your treatment for three years. Your doctor will continue to monitor your cerebrospinal fluid levels with spinal taps every six months. Neurosyphilis is especially common in HIV-positive people. This is because syphilitic sores make it easier to become infected with HIV. The Treponema pallidum bacteria interact with HIV in a way that makes it harder to treat the syphilis infection. Those with neurosyphilis who are HIV-positive usually need more penicillin injections and have less chance for a complete recovery.
Answered 8/19/2014
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