A 49-year-old male asked:
since being on cymbalta (duloxetine) 60 mg. 2 months very hyper...also take tegretol -klonopin-lamictal...if i go back to 30 how long til steady state.is this rare?
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Cymbalta (duloxetine) hypo mania: This is not rare at all. We are learning to rely less on antidepressants in bipolar disorder because of this. Antidepressants, especially snri's like Cymbalta and Effexor may cause more mood switching than most. Wellbutrin is said to cause it the least. The issue is not the steady state, but whether this effect will continue even at 30 mg a day. Latuda (lurasidone) is approved for treatment of BP depression.
Answered on May 7, 2016
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