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A 49-year-old male asked:

Take cymbalta (duloxetine) 60, lamictal 100, tegretol 600, klonopin 2.5 for ocd and mood..is this a safe combination..and is 60 the usual dose for cymbalta (duloxetine)?

2 doctor answers3 doctors weighed in
Dr. Donald Jacobson
A Verified Doctoranswered
42 years experience
Combo is safe: Cymbalta (duloxetine) 60 mg is the average dose, but can go up to 120 mg per day. Your doctor is juggling a lot of drug-drug interaction potentials, but the doses all look good. Glad you had the allergy testing. Sounds like you are getting very knowledgeable and competent care. Avoid alcohol and grapefruit because they will both greatly effect the blood levels of your medications. Enjoy the weekend! by the wayyour profile says that you are on luvox.
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Dr. Patrick Tapia
Psychiatry 15 years experience
Seems fine: These dosages seem to be workable although it is an intense combination of mood stabilizers. The dose of duloxetine at 60 mg is at the usual amount for the treatment of a mood disorder although higher dosages are thought to be potentially helpful for the treatment of chronic pain. Stay safe!
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Mar 18, 2022

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