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A 33-year-old member asked:

what are causes of primary bone lymphoma?

1 doctor answer3 doctors weighed in
Dr. Myron Arlen
Surgical Oncology 64 years experience
Viral: It appears that lymphoma, especially in bone marrow arises from viral transfection of the Wnt-1 gene. This occurs in 3 systems, that is the invasion of the MMTV virus into the cells of the milk duct of the breast, the cells of the prostate and the lymphocyte. The Wnt-1 gene then turns on overexpression of B catenin which leads to the transformation to malignancy.

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A 34-year-old member asked:

What leads to primary bone lymphoma?

1 doctor answer2 doctors weighed in
Dr. Agos Luca
Dr. Agos Luca answered
Specializes in Pathology
Hard to say...: Most of the times we don't know what exactly causes lymphoma so there isn't much we can do to prevent it. Most cases probably have a genetic component but the process is probably multifactorial and many other things need to happen in order to produce lymphoma. In a small subset of cases, a distinct cause appears to exist: exposure to toxins, radiation, certain viruses (ex: ebv).

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Last updated Oct 24, 2017
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