A member asked:

Is it safe to take ibuprofen with metoprolol, lisinopril hctz, (hydrochlorothiazide) and klor-con 10?

7 doctors weighed in across 4 answers
Dr. John Mcpherson answered

Specializes in Internal Medicine - Cardiology

Ibuprofen is generally well tolerated but can worsen high blood pressure and kidney function. Since you are on multiple medications that can effect blood pressure and kidney function, i would check with your doctor first before taking Ibuprofen regularly.

Answered Nov 18, 2020



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Dr. Ronald Krauser answered

Specializes in Rheumatology

With hypertension you need to monitor your BP and kidney function if you take it regularly.

Answered Jun 10, 2014


Dr. John Munshower answered

Specializes in Family Medicine

In moderation, Ibuprofen is safe with those medications. Ibuprofen like all nsaids does go through the kidneys as does Lisinopril and hctz, (hydrochlorothiazide) so very prolonged use of the Ibuprofen is not recommended at is may cause kidney damage. Best wishes.

Answered Feb 3, 2020


Dr. Jerome Zacks answered

Specializes in Cardiology

However, taking an NSAID such as Ibuprofen for a prolonged period can cause salt retention, hypertension, heart failure and stomach ulcers.

Answered Dec 1, 2014



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