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A 29-year-old female asked:

Is it safe to take ibuprofen with metoprolol, lisinopril hctz, (hydrochlorothiazide) and klor-con 10?

4 doctor answers7 doctors weighed in
Dr. John Mcpherson
Internal Medicine - Cardiology 29 years experience
Not always: Ibuprofen is generally well tolerated but can worsen high blood pressure and kidney function. Since you are on multiple medications that can effect blood pressure and kidney function, i would check with your doctor first before taking Ibuprofen regularly.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Ronald Krauser
A Verified Doctoranswered
Rheumatology 53 years experience
Yes, but: With hypertension you need to monitor your BP and kidney function if you take it regularly.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. John Munshower
Family Medicine 31 years experience
Yes: In moderation, Ibuprofen is safe with those medications. Ibuprofen like all nsaids does go through the kidneys as does Lisinopril and hctz, (hydrochlorothiazide) so very prolonged use of the Ibuprofen is not recommended at is may cause kidney damage. Best wishes.
Created for people with ongoing healthcare needs but benefits everyone.
Dr. Jerome Zacks
Cardiology 52 years experience
Yes, briefly: However, taking an NSAID such as Ibuprofen for a prolonged period can cause salt retention, hypertension, heart failure and stomach ulcers.
Created for people with ongoing healthcare needs but benefits everyone.
Last updated Nov 18, 2020

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