A member asked:

Can vancomycin cause c diff infection?

3 doctors weighed in across 2 answers

Possible, unlikely: Vancomycin is seldom taken orally, and when it is it can at least partially treat c. Difficile infection, although it isn't active against spores. When taken IV it is primarily excreted by the kidneys and little is likely to get into the distal colon unchanged. If it did it will not alter flora significantly and predispose to cl. Difficile overgrowth or toxin production by the vegetative form.

Answered 3/1/2019

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Dr. Donald Alves answered

Specializes in Emergency Medicine

Usually not: Vancomycin orally treats c.Diff. Intravenous vancomyin might disrupt the bacterial flora and lead to overgrowth.

Answered 3/1/2019

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