My orthopedic held my hand while i fell asleep for surgery, is that weird?

not really: It sounds like you may have been visably anxious. If you feel it was not comforting or that it was improper; use another doctor for any future knee problems. Remember he was not alone with you during surgery and that the staff and anesthesia provider was also there.

No: No it's not i think it shows concern and caring on the part of your ors.