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What happens if you stop taking methotrexate suddenly

A 44-year-old member asked:
Dr. John Michalski
Orthopedic Surgery 36 years experience
Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard.

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A 32-year-old member asked:
Dr. Tariq Niazi
Orthopedic Surgery 43 years experience
Depends on your RA -: Being controlled or not. Your symptoms might get worse. You should check with your rheumatologists as they might change it for some other medicine or... Read More
A 37-year-old member asked:
Dr. Bruce Rothschild
Rheumatology 48 years experience
possible flare: Possibly may cause flare, but depends on why stopping. If significant side effect, that outweighs the flare risk.
A member asked:
Dr. Lynn Greenhouse
Internal Medicine 29 years experience
No: There is no evidence that most multivitamins will be either helpful or harmful in combination with methotrexate. However it is very important that yo... Read More
A female asked:
Dr. John Goldman
Rheumatology 55 years experience
Rapidly leaves: 1/2 life depends on dose 3-10 hours with low dose and 8-15 hours with high dose We usually say it is out after 5 1/2 lives bt there are tissue ... Read More
A 23-year-old female asked:
Dr. Eduardo Ibarguen-secchia
Pediatric Gastroenterology 38 years experience
Could be Crohn's: Some of the most common side effects can be similar to symptoms of crohn's. These include mouth sores, fever, diarrhea, blood in your stools, body ach... Read More
A female asked:
Dr. Tracy Lovell
Rheumatology 21 years experience
Azathioprine or plaq: Plaquenil (hydroxychloroquine) is the safest to be on for pregnancy and in severe lupus we use azathioprine as it not as toxic to a fetus. Talk to yo... Read More
A 34-year-old female asked:
Dr. John Goldman
Rheumatology 55 years experience
May or may not: it may not make you have a normal cycle. This is something you can ask your physician. You may need to do discuss this with the gynecologist.
A 39-year-old member asked:
Dr. Michael Sparacino
Family Medicine 37 years experience
See below: He/she may experience a flare in his/her symptoms. Let the doctor know what's going on.
A 23-year-old male asked:
Dr. Steven Simon
A Verified Doctoranswered
A US doctor answeredLearn more
Probably yes: The operating surgeon will direct you in the correct answer. These medicines may change immune system or risk of bleeding, but only the surgeon has th... Read More

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