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what happens if you stop taking methotrexate suddenly

A 52-year-old member asked:
Dr. John Michalski
35 years experience Orthopedic Surgery
Methotrexate: You will likely have more swelling, pain, & stiffness, unless you are taking another med or dmard.
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A 39-year-old member asked:
Dr. Tariq Niazi
42 years experience Orthopedic Surgery
Depends on your RA -: Being controlled or not. Your symptoms might get worse. You should check with your rheumatologists as they might change it for some other medicine or ... Read More
A 44-year-old member asked:
Dr. Bruce Rothschild
47 years experience Rheumatology
possible flare: Possibly may cause flare, but depends on why stopping. If significant side effect, that outweighs the flare risk.
A member asked:
Dr. Lynn Greenhouse
28 years experience Internal Medicine
No: There is no evidence that most multivitamins will be either helpful or harmful in combination with methotrexate. However it is very important that yo ... Read More
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A 33-year-old male asked:
Dr. Pamela Pappas
41 years experience Psychiatry
SSRI Discontinuation: Citalopram is an ssri antidepressant. If you stop it or any of its relatives suddenly, you may experience discontinuation (withdrawal) symptoms. The ... Read More
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A 39-year-old member asked:
Dr. Lance Anderson
24 years experience Psychiatry
Discontinuation: Stopping an ssri abruptly can cause a "discontinuation syndrome" which can be very uncomfortable. People can experience this as physical symptoms, em ... Read More
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A 63-year-old male asked:
Dr. John Goldman
54 years experience Rheumatology
Long time: Plaquenil (hydroxychloroquine) takes a long time to get out of the system - up to 18 months. Be certain you and your physician agree you should disco ... Read More
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A 51-year-old member asked:
Dr. Robert Berkowitz
33 years experience Psychiatry
Withdrawal: Technically, we use the term discontinuation syndrome to describe what happens on sudden withdrawal from sertraline or other ssri. Symptoms include i ... Read More
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A 51-year-old member asked:
Dr. Neil Liebowitz
38 years experience Psychiatry
Depends: If on a higher dose eg 200mg or more. There is an increased risk of seizure. My patient who feel it is helping report that they feel acutely anxious ... Read More
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A 47-year-old member asked:
Dr. Bernadette Onuoha
37 years experience Psychiatry
Could be a bad idea: Suddenly stopping your antidepressant medication could lead to serious problems called discontinuation syndrome and it is no pleasant at all. Talk to ... Read More
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A 54-year-old member asked:
Dr. Tracy Lovell
20 years experience Rheumatology
Could: If you have been on Prednisone for a long time, you could precipitate adrenal insufficiency. Talk to your before abruptly stopping any medication.
A 44-year-old member asked:
Dr. Michael Thompson
19 years experience Hematology and Oncology
Tobacco bad: There are many reasons not to smoke, but i don't know of a specific interaction between smoking and rituximab.
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A 50-year-old member asked:
Dr. Jeffrey Desarbo
19 years experience Psychiatry
Serotonin Effects: Some people experience what is known as serotonin discontinuation syndrome which is like withdrawal. Symptoms include dizziness, sweating, nausea, agi ... Read More
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A 51-year-old member asked:
Dr. Frederick Singer
57 years experience Endocrinology
Hypothyroidism: If you are taking levothyroxine because of hypothyroidism you will develop fatigue, constipation and weight gain over time and perhaps other symptoms.
A 50-year-old member asked:
Dr. Walter Futterweit
63 years experience Endocrinology
If acne recurs, Rx: Effect on acne helps with Accutane. If recurs, ant-androgens help the acne.
A 54-year-old member asked:
Dr. Susan Wingo
32 years experience Endocrinology
Low thyroid levels: Most people need to thyroid hormone(th) forever because their thyroid can't make enough. Stopping th leads to low thyroid levels, and feeling cold, s ... Read More
A 69-year-old female asked:
Dr. Ed Friedlander
43 years experience Pathology
Can die: Big doses of Prednisone shrink your adrenal cortices. If you stop all at once, and you have some stressor that required cortisol production, and you d ... Read More
A 32-year-old female asked:
Dr. Bernadette Onuoha
37 years experience Psychiatry
Could be a bad idea: Suddenly stopping your ssri could lead to serious problems called discontinuation syndrome and it is no pleasant at all. Talk to your prescribing doct ... Read More
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A 32-year-old female asked:
Dr. Ladislav Volicer
61 years experience Geriatric Psychiatry
You might feel bad: Common responses to dose reduction or cessation of ssris include dizziness, electric shock-like sensations, sweating, nausea, insomnia, tremor, confus ... Read More
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A 42-year-old female asked:
Dr. Dan Fisher
26 years experience Internal Medicine
Depends: With some antidepressants you can get an unpleasant withdrawal syndrome if you stop them suddenly. With others it is not so bad. In either case under ... Read More
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A 73-year-old male asked:
Dr. Robert Lowe
16 years experience Pediatric Rheumatology
Flare of arthritis: If you stop your remicade, (infliximab) you will be at significant risk for a bad flare of your arthritis. You should only stop arthritis medication o ... Read More
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A 56-year-old member asked:
Dr. Samuel Freedman
8 years experience Pediatrics
Hypothroidism: You become hypothyroid. Symptoms include dry skin, coarse hair, constipation fatigue cold intolerance forgetfulness depression mood swings allopecia.

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