Q: lupus anticoagulant eval. the ref range is <45sec. does the result matter if its over 45? for example, is a result of 51 more indicative of an issue than 46? if the la screen and drvvt screen is high and confirm is - what factors should be checked?

: Pleas touch base with the doctor who ordered the test. Background &amp; context is needed.

Q: had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? factor 5 also runs in my family.

Normally: a factor V deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time.

Q: how common is an elevated lupus anticoagulant level in a 4 year old girl?

Not common, but can.: It can occur. However, it would be much rarer for your four year old to have sle. Antiphospholipid syndrome can occur by itself, or with other conditions.

Q: lupus anticoagulant screen w/ reflex. is it normal for the results to change/worsen in 5 months? first time in october the drvvt confirmation was negative. 5 months later it was positive. both times had a high drvvt screen. why would results change?

: Tests for LA need to be confirmed after 3 months because medication(s) or some clinical events, e.g. infection, can affect the result.

Q: my pcp ordered a lupus screen. lupus anticoagulant screen was 31. drvvt was 47(standard range under 45). drvvt 1:1 negative. what does this mean? is it concerning that my drvvt was high? i will talk to my dr. i have 4 other autoimmune dis?

: This is a test for the presence of the lupus anticoagulant. Since your DRVVT ratio was normal, I doubt that the borderline reading of 47 is significant. When it's elevated the lab usually reflexively tests other coagulation tests for more information. The rheumatologist can advise you best as he/she knows your clinical history &amp; findings.

Q: had lupus anticoagulant eval w/reflex done twice in 3 months. 1st drvvt screen high. 2nd screen high, confirmation positive, mix corrected. what factor deficiency can cause these results? how would you interpret these results-weak la or factor def?

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, there is not sufficient information in your message to provide a meaningful response. Wish you good health!

Q: a lupus anticoagulant is detected since one of the two confirmatory tests is positive.hexagonal phase confirm -positive - what does it mean? also high alpha-1, low albumin, high alkaline phosphate, crp lvl 31, high absolute neutros,lymphocs,eosinos

Lab tests: Please ask the physician that ordered them to explain the results to you as the lab results should only be used in conjunction withe the history and physical examination. Good Luck

Q: anti phospholipid igg was mildly elevated and esr was 71. lupus anticoagulant was negative. crp was high normal. had bad sinus infections.worry?

Not about this: Huge numbers of otherwise-healthy people have low-titer antiphospholipid antibodies. The C-reactive protein is of some use in specific circumstances, and is high in advanced atherosclerosis which I trust you do not have. I'd be thankful for good health and address the sinus and facial pain issues. Best wishes.

Q: what tumors can cause lupus anticoagulant?

Several: Several tumors can cause the anticoagulant with lung cancer one of the most common.

Q: need information on circulatory lupus anticoagulant?

See below: It is an immunoglobulin that binds to protein and phospholipids of the cell membrane.In fact it can be prothrombotic unless treated with an anticoagulant such as coumadin!

Question 1

lupus anticoagulant eval. the ref range is <45sec. does the result matter if its over 45? for example, is a result of 51 more indicative of an issue than 46? if the la screen and drvvt screen is high and confirm is - what factors should be checked?

Accepted Answer

: Pleas touch base with the doctor who ordered the test. Background &amp; context is needed.

Question 2

had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? factor 5 also runs in my family.

Accepted Answer

Normally:  a factor V  deficiency can cause a prolonged thrombin time But your bleeding time and platelet count should be unaffected. Certain medications and other diseases could also cause elevated thrombin time.

Question 3

how common is an elevated lupus anticoagulant level in a 4 year old girl?

Accepted Answer

Not common, but can.: It can occur.  However, it would be much rarer  for your four year old to have sle.  Antiphospholipid syndrome can occur by itself, or with other conditions.

Question 4

lupus anticoagulant screen w/ reflex. is it normal for the results to change/worsen in 5 months? first time in october the drvvt confirmation was negative. 5 months later it was positive. both times had a high drvvt screen. why would results change?

Accepted Answer

: Tests for LA need to be confirmed after 3 months because medication(s) or some clinical events, e.g. infection, can affect the result.

Question 5

my pcp ordered a lupus screen. lupus anticoagulant screen was 31. drvvt was 47(standard range under 45). drvvt 1:1 negative. what does this mean? is it concerning that my drvvt was high? i will talk to my dr. i have 4 other autoimmune dis?

Accepted Answer

: This is a test for the presence of the lupus anticoagulant. Since your DRVVT ratio was normal,  I doubt that the borderline reading of 47 is significant. When it's elevated the lab usually reflexively tests other coagulation tests for more information.  The rheumatologist can advise you best as he/she knows your clinical history &amp; findings.

Question 6

had lupus anticoagulant eval w/reflex done twice in 3 months. 1st drvvt screen high. 2nd screen high, confirmation positive, mix corrected. what factor deficiency can cause these results? how would you interpret these results-weak la or factor def?

Accepted Answer

: All laboratory results need to be interpreted in the clinical context and the doctor who ordered the tests is usually in the best position to do that. Talk to the doctor who ordered the tests. Having said that, there is not sufficient information in your message to provide a meaningful response.    Wish you good health!

Question 7

a lupus anticoagulant is detected since one of the two confirmatory tests is positive.hexagonal phase confirm -positive - what does it mean? also high alpha-1, low albumin, high alkaline phosphate, crp lvl 31, high absolute neutros,lymphocs,eosinos

Accepted Answer

Lab tests: Please ask the physician that ordered them to explain the results to you as the lab results should only be used in conjunction withe the history and physical examination. Good Luck

Question 8

anti phospholipid igg was mildly elevated and esr was 71. lupus anticoagulant was negative. crp was high normal. had bad sinus infections.worry?

Accepted Answer

Not about this: Huge numbers of otherwise-healthy people have low-titer antiphospholipid antibodies. The C-reactive protein is of some use in specific circumstances, and is high in advanced atherosclerosis which I trust you do not have. I'd be thankful for good health and address the sinus and facial pain issues. Best wishes.

Question 9

what tumors can cause lupus anticoagulant?

Accepted Answer

Several: Several tumors can cause the anticoagulant with lung cancer one of the most common.

Question 10

need information on circulatory lupus anticoagulant?

Accepted Answer

See below: It is an immunoglobulin that binds to protein and phospholipids of the cell membrane.In fact it can be prothrombotic unless treated with an anticoagulant such as coumadin!

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Doctor answers about:

High la1 la2 ratio lupus anticoagulant

A member asked:

Lupus anticoagulant eval. the ref range is <45sec. does the result matter if its over 45? for example, is a result of 51 more indicative of an issue than 46? if the la screen and drvvt screen is high and confirm is - what factors should be checked?

A member asked:

Had a lupus anticoagulant test done all was normal except for a high thrombin time at 22.8 is this serious? factor 5 also runs in my family.

A member asked:

How common is an elevated lupus anticoagulant level in a 4 year old girl?

A member asked:

Lupus anticoagulant screen w/ reflex. is it normal for the results to change/worsen in 5 months? first time in october the drvvt confirmation was negative. 5 months later it was positive. both times had a high drvvt screen. why would results change?

A member asked:

My pcp ordered a lupus screen. lupus anticoagulant screen was 31. drvvt was 47(standard range under 45). drvvt 1:1 negative. what does this mean? is it concerning that my drvvt was high? i will talk to my dr. i have 4 other autoimmune dis?

A member asked:

Had lupus anticoagulant eval w/reflex done twice in 3 months. 1st drvvt screen high. 2nd screen high, confirmation positive, mix corrected. what factor deficiency can cause these results? how would you interpret these results-weak la or factor def?

A member asked:

A lupus anticoagulant is detected since one of the two confirmatory tests is positive.hexagonal phase confirm -positive - what does it mean? also high alpha-1, low albumin, high alkaline phosphate, crp lvl 31, high absolute neutros,lymphocs,eosinos

A member asked:

Anti phospholipid igg was mildly elevated and esr was 71. lupus anticoagulant was negative. crp was high normal. had bad sinus infections.worry?

A member asked:

What tumors can cause lupus anticoagulant?

A member asked:

Need information on circulatory lupus anticoagulant?

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