A member asked:

How does the bun/creatinin ratio relate to the egfr? both of these levels are low but both the bun and creatinin levels were right in the mid range.

6 doctors weighed in across 3 answers
Dr. S. Smiley Thakur answered

Specializes in Nephrology and Dialysis

Co-tango usually: The BUN is usually 10 times the creatinine. When the creatinine goes up, the BUN goes up similarly to roughly keep this proportion, in most kidney disease states. The notable exception is when the creatinine goes up say by 20% to 1.2, but the BUN goes up *5 to 50. This strongly suggests a pre-renal state, commonly dehydration. Mild elevations of BUN with normal creatinines aren't of concern.

Answered 9/24/2016

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Ignore it: It's not real. I'd urge you to ignore your "estimated gfr" provided by some labs. It's subscience -- for example, it even includes an adjustment for race "because black people are more muscular than white people." it's really intended only for people whose kidneys are already clearly gone bad.

Answered 9/30/2013

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EGFR explanation: Egfr is simply how many milliliters of blood do your kidneys process per minute. Normal egfr is above a 100 and anything over 60 ml/min is still great. Egfr gets calculated from a mathematical formula that takes into account your age, weight, sex, race and creatinine. So if your creatinine is in the midrange, the other factors may make egfr low anyway. BUN and bun/cr ratio are irrelevant here.

Answered 6/10/2014

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