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A member asked:
What are the differences between prozac and cymbalta (duloxetine)?
7 doctors weighed in across 2 answers
Prozac (fluoxetine) lasts longer: Prozac primarily blocks serotonin reuptake. Cymbalta (duloxetine) blocks norepinephrine & serotonin reuptake. Prozac lasts up to 2 wks in your system after the last dose. Cymbalta (duloxetine) also is used to treat pain & depression. Prozac can help for some anxiety disorders, bulimia & depression. It has variable efficacy in borderline personality disorder.
Answered 6/27/2018
4.9k views
Norepeniphrine: Prozac increases only serotonin while Cymbalta (duloxetine) increase both serotonin and norepinephrine. Never quit Cymbalta (duloxetine) suddenly or you could feel really lousy...
Answered 1/31/2020
4.9k views
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