A member asked:

Is there a way to go off cymbalta (duloxetine) by just switching completely over to prozac the first day and continuing with prozac?

4 doctors weighed in across 2 answers

Yes: Prozac has a long half life and will counter the side effects of Cymbalta (duloxetine) withdrawal.

Answered 5/14/2018

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Dr. Heidi Fowler answered

Specializes in Psychiatry

To avoid: Ssri discontinuation symptoms while making the change - a cross titration could be useful. In other words, reducing the dose of one while increasing the dose of the other. And doing this progressively until you are off the first medication and you get to the target dose of the second medication.

Answered 4/17/2016

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