Will my friend die if he took a whole bottle of mirtazapine with a few drinks?

Call an emergency : Call an emergency room and ask the triage nurse. I am a psychologist not an md but do not want you to wait on a saturday night for a response. Don't wait call right away to get an answer from someone near you.

Not definitely: Overdoses are dangerous and each medication has its own side effects. Your friend may become very drowsy and should seek help at an emergency department. There he can receive treatment to help alleviate symptoms and observe for catastrophe.

Call 911: If you know someone is attempting or capable of harming themselves you call the 911 emergency system and report this. The cops then have a right to get this person to the hospital. You can save a life if you act urgently.

Call 911 go to er: This is an emergency. Your friend needs to be evaluated asap in an emergency room setting. Once he/ she issafe and stable the why and how need to be looked at as well. But life safety first.