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A member asked:

It it possible for one with lupus to have flare if labs (other than ana) are normal?or will most rheummds discount that "flare" if neg labs & exam?

A doctor has provided 1 answer

SLE: Yes, anything that may trigger some stress or sunlight exposure most definitely incites your flare ups. Ask your dr. For methods to help prevent flare ups even with nl labs.

Answered 8/24/2013

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Can someone explain 2 me how i can feel terrible with lupus even when my inflammatory markers & other labs (other than high ana) are currenlty normal ?

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Dx 9/12 uctd using injectable mtx since. Esr 99/crp 44.64 has steadily risen x 10 mos. Ana & RA neg. Is it poss. To still have ra/ lupus w/ neg labs?

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Recur s/s worse recently fatigue joint pain/ rash- face and top of hands,raynauds/chilblains labs pos ANA titer pattern homogeneous. SOB/pain left rib protein in UA. EGFR 82. ST prednisone taper 120mg s/s better. dsdna- 25 iu/ml (neg?) Not lupus?

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A member asked:

Do mds know pathophysiology of lupus fatigue requiring frequent napswhen labs (other than very high ana)are currently normal?(didn't have before lupus

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Can I still possibly have drug induced lupus with a negative ANA and normal anti histone ? All symptoms point to it but all labs negative. I do Take high risk Medications?

A doctor has provided 1 answer

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Malar rash,photosensitivy,sicca ,mouth/nose sores,Recurring flares, leukopenia, ANA 1:640.All other labs neg.Rhuem dx'd lupus.Possible w/normal labs?
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