Are there safe alternative therapies for paget's disease of breast?

Surgery is necessary: Pagets disease of the breast is a condition that requires definitive surgery +/- radiation to the breast to prevent it from becoming a locally advanced process. Most people can undergo a lumpectomy that includes removing the nipple-areola complex, followed by a course of breast radiation. You should see a breast surgeon for a full discussion.

No: Pagets disease of the breast is breast cancer and should be treated like all other breast cancers.