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A member asked:
Is evidence of elevated mao enzymes in the brains of clinically depressed people a biological marker of major depression?
7 doctors weighed in across 2 answers
Depression: No tests to diagnose depression. It is a clinical diagnosis means by seeing the patient asking question and mental status exam done by a doc.
Answered 11/27/2017
5k views
Some say yes: The monoamine hypothesis of depression posits the synaptic metabolism of monoamine neurotransmitters as one of the principal determinants of mood. It seems to be a useful heuristic although undoubtedly there are additional impinging variables. A gain of function mutation in monoamine oxidase may lead to excessive catabolism of monoamine neurotransmitters for retention of stable mood. Stay safe!
Answered 10/20/2013
4.8k views
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