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South Africa
A 22-year-old male asked:

Ever since i started clozapine i've been drooling. how long until it goes away or is it here to stay?

2 doctor answers3 doctors weighed in
Dr. Pamela Pappas
Psychiatry 42 years experience
Drooling & Clozaril (clozapine): Drooling is a known side effect of clozaril, (clozapine) and it may be dose-related. Talk with your doctor about this, to see if the dose can be adjusted. Clozaril (clozapine) can be very helpful for disabling psychotic symptoms, and your need for this must be balanced against any side effects. I'm sure your doctor wants the best for you.
Dr. Heidi Fowler
Psychiatry 25 years experience
Clozapine: Sialorrhea (excessive drooling) can occur in 30 to 80% of people taking clozapine. It may not decrease. Although usually dose independent, lowering dose may decrease sx. Atropine or Glycopyrolate may help. Tell your dr. if it is causing gagging. REF: https://www.thenationalcouncil.org/wp-content/uploads/2017/04/Clozapine-Webinar-3-.pdf?daf=375ateTbd56

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South Africa
A 22-year-old male asked:

Since i started clozapine i've been very lethargic and drooling a waterfall. How long until it goes away?

2 doctor answers3 doctors weighed in
Dr. Alan Ali
Dr. Alan Alianswered
Psychiatry 32 years experience
Clozapin: Lethargy is dose-related. Side effects need to be reviewed with your prescribing doctor.

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Last updated Jan 10, 2021

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