A member asked:

Ever since i started clozapine i've been drooling. how long until it goes away or is it here to stay?

3 doctors weighed in across 2 answers
Dr. Pamela Pappas answered

Specializes in Psychiatry

Drooling & Clozaril (clozapine): Drooling is a known side effect of clozaril, (clozapine) and it may be dose-related. Talk with your doctor about this, to see if the dose can be adjusted. Clozaril (clozapine) can be very helpful for disabling psychotic symptoms, and your need for this must be balanced against any side effects. I'm sure your doctor wants the best for you.

Answered 1/10/2021

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Dr. Heidi Fowler answered

Specializes in Psychiatry

Clozapine: Sialorrhea (excessive drooling) can occur in 30 to 80% of people taking clozapine. It may not decrease. Although usually dose independent, lowering dose may decrease sx. Atropine or Glycopyrolate may help. Tell your dr. if it is causing gagging. REF: https://www.thenationalcouncil.org/wp-content/uploads/2017/04/Clozapine-Webinar-3-.pdf?daf=375ateTbd56

Answered 1/10/2021

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