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A 22-year-old male asked:

How long after being on clozapine does its sedating effects go away? i'm supposed to take it in the morning too but it's way too sedating so i don't.

1 doctor answer1 doctor weighed in
Dr. Heidi Fowler
Psychiatry 26 years experience
Sedation: Please see article “Sedation side effect of clozapine”. REF: https://smiadviser.org/knowledge_post/sedation-side-effect-with-clozapine. Sedation can increase with each dose increase. It does tend to decrease over time (but I can't say how long that takes). People often take it at night if overly sedated or drink something like coffee if too sedated in morning.
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Last updated Jan 10, 2021

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