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A member asked:
What would your next step in po treatment be for mrsa superficial skin infection in a patient who doesn't respond to mupirocin topical 2% in 3 days?
14 doctors weighed in across 2 answers
Cotrimoxazole: Trimethoprim sulfamethoxazole (bactrim (sulfamethoxazole and trimethoprim) or septra) may help to eliminate the acute infection, assuming it is due to strain usa 300. They can also be treated prophylactically to try to eliminate skin carriage using Mupirocin in the nares bid for several weeks and bathing solely with a Chlorhexidine containing soap.
Answered 10/6/2017
5k views
See below: I would usually use septra/bactrim first, Doxycycline second and Clindamycin third and would want sensitivity data. Linezolid would be reserved for more serious outpatient infection treatment because of its expense and high risk of causing c. Difficile overgrowth.
Answered 9/24/2017
5k views
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