A member asked:

Is it better to take isosorbide mononitrate 10 mg tab before bed or in the morning ? will it last long enough to cover me during sleep? i have coronary vasospasm/micro vascular angina and history of v tach?

2 doctors weighed in across 2 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

For prophylactic purpose you should take it twice a day. Good luck.

Answered 6/4/2023

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With a half life of only 5 hours, I don't think that taking ISMO only once daily will adequately cover you for variant angina or coronary vasospasm for 24 hours. Discuss this with your cardiologist who knows you best though.

Answered 6/4/2023

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