A member asked:

Hi, i've been taking sulfasalazine (500 mg in morning and 500 mg at night) for 2.5 months. i have a dental surgery (apicectomy) scheduled in the next week. can i take ibuprofen for pain after the surgery, every 8 hours for 3-4 days?

3 doctors weighed in across 2 answers

It should not affect your sulfa. just dont take them together Hope you do well

Answered 5/31/2023

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Dr. Neil McLeod answered

Specializes in Prosthodontics

There is a moderate interaction between sulfasalazine and ibuprofen. Taking these medications together may increase the risk of gastrointestinal side effects such as bleeding or ulcers. Sulfasalazine is used to treat inflammatory bowel disease and rheumatoid arthritis. Ibuprofen is a nonsteroidal anti-inflammatory drug (NSAID) that is commonly used for pain relief. It is important to consider this

Answered 6/2/2023

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