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This is for my mother, aged 55. High serum kappas (33), normal lambdas and marginally high kappa lambda ratio (1.9). SPEP and Immunofixation show polyclonal gammopathy (in IgG Kappa and Lambda). Should we be concerned about MGUS/Myeloma ?
Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.
An apparent polyclonal gammopathy: IgA. Kappa and lambda typing appear increased. What does this mean? Im being referred to a Hematologist, Do I have Cancer?
My total protein had been increasing, so my dr had me test for multiple myeloma. Protein had come down to normal,no m-spike observed, everything normal except a slightly elevated kappa of 21.5 in serum (but normal in urine). Could I still have cancer?
Kappa/lambda FLC ratio high (2.75) w/ normal K(10.21mg/dl) & low L(3.68mg/dl). Hem-onc unsure if ratio implies K monoclonality since serum/urine IFE ok & neither chain is elevated. Could monoclonal K be suppressing L? IgA a bit high IgG &IgM a bitlow
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