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A member asked:
I am 45 and male. serum iga at 472 mg/dl and an apparent polyclonal gammopathy iga kappa/lambda typing appear increased. serum free light chain: high kappa 35 mg/l, lambda normal 17.8 mg/l and a ratio of 1.97. is this myeloma? no m-protein found?
A doctor has provided 1 answer
For accurate diagnosis you need a good history and physical by your dopc. Pl do that
Answered 4/16/2023
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Free kappa light chain is high, FLC ratio is 2.205, no monoclonal gammopathy. IgA 389.43, lgM 125.95 and lgG 1771.02 H. Should we be worried? Thanks.
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This is for my mother, aged 55. High serum kappas (33), normal lambdas and marginally high kappa lambda ratio (1.9). SPEP and Immunofixation show polyclonal gammopathy (in IgG Kappa and Lambda). Should we be concerned about MGUS/Myeloma ?
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