A member asked:

In terms of safety / least toxicity, would posaconazole, itraconazole, or voriconazole be a better choice for fluconazole-resistant infection?

A doctor has provided 1 answer
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

By UPTODATE: "agents within the azole class vary importantly with regards to spectrum of activity, pharmacokinetic profiles, and toxicities. It is important for clinicians to appreciate the unique characteristics of each member of this class in order to use azoles appropriately". So we should concentrate on the fungal species to treat for choosing the azole rather than worrying about side effects

Answered 1/15/2023

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