A member asked:

Five year old had an mri due to a seizure. tiny focal area of increased flair signal involving the anterolateral right frontal white matter which is nonspecific however may reflect minimal gliosis... what does that mean? is it a concern?

5 doctors weighed in across 3 answers
Dr. Hiep Le answered

Specializes in Nephrology and Dialysis

What other symptoms did this child have besides seizure? Did he (she) have evidence of systemic infection and other neurological symptoms such as lethargy, somnolence, nausea/vomit, etc. Those symptoms can help us to associate with the MRI findings. I would say a thorough discussion with the pediatrician and the neurologist is warranted. It's always a concern when a 5-year-old-child has a seizure.

Answered 6/26/2022

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Dr. Amrita Dosanjh answered

Specializes in Pediatric Allergy and Asthma

Gliosis is commonly associated with a variety of brain disorders. The inflammation/irritation of the tissue around a lesion or seizure focus are examples. Please discuss whether there is any brain mass or lesion see on the MRI and whether the scan is sufficient to detect a brain mass or lesion. Seizures are more frequent with a fever and fever control measures while ill are usually advisable.

Answered 6/27/2022

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The tiny area of gliosis may or may not represent a seizure focus and more likely is a coincidental benign lesion. A pediatric neurologist can assist further evaluation and management. Key is risk of future additional seizure activity.

Answered 7/1/2022

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