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A 50-year-old female asked:

Due to a chronic illness, i have been taking some kind of opioid &had constipation for 15yrs. ive used stool softeners, laxatives, enemas & suppositories. these rarely work anymore. i will go weeks without having a bm. im scared. any suggestions?

1 doctor answer1 doctor weighed in
Dr. Hiep Le
Dr. Hiep Leanswered
Nephrology and Dialysis 44 years experience
For patients with opioid-induced constipation who do not respond to laxatives, naldemidine (Symproic) and naloxegol (Movantik) have a strong recommendation for use, with methylnaltrexone (Relistor) having a conditional recommendation. You should check this link for more info: https://www.drugs.com/answers/support-group/opioid-induced-constipation/
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Last updated Apr 22, 2022


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