I have never had a patient complain of fatigue soon after having a corticosteroid injection into shoulder,hip,knee,wrist etc but it definitely has been reported. Some speculate that it's caused by fluctuations of blood sugar. If the fatigue persists see your MD for evaluation including some basic blood testing such as cbc&diff, glucose,electrolytes, creatinine thyroid panel.
Answered 4/2/2022
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