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A member asked:
Does methotrexate for psoriasis cause damage or modification to the dna in the long term?
A doctor has provided 1 answer
There is some evidence that methotrexate causes DNA damage at dosages used for chemotherapy of cancer -- but the dosages used to treat psoriasis are much lower, and there are no reports of DNA damage at those lower doses that I am aware of.
Answered 1/3/2022
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