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A member asked:
Can methotrexate treat psoriasis?
5 doctors weighed in across 2 answers
Yes: Yes, it is one of many treatments available to patients with psoriasis. A dermatologist should be able to tell if it is appropriate for any particular patient. It has been used for decades, so we have a lot of experience with this drug.
Answered 4/16/2015
5.5k views
Yes. Agree, but....: Methotrexate can be very effective. However, the first studies raising the specter of liver disease came from psoriasis patients on daily low dose oral mtx!. The first pass effect is dangerous for the liver. Mtx cannot be adjudicated aqs an oral drug. Absorption is variable (40-90%), causes GI upset, and hits the liver first. I only use subcutaneous mtx once weekly. This is the safest!
Answered 1/21/2019
5.5k views
Related Questions
A member asked:
Does methotrexate work well to help with psoriasis?
2 doctors weighed in across 2 answers
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What are the side effects of methotrexate for psoriasis worth taking the risk?
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A member asked:
Does methotrexate for psoriasis cause damage or modification to the DNA in the long term?
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A member asked:
My Dr. wants me back on methotrexate b/c of inflammation levels in my body. Whats your opinion on inflammation in the body & psoriasis?
4 doctors weighed in across 3 answers
A member asked:
My age is 29yrs. For psoriasis, i'm taking methotrexate 7.5 mg since 7yrs. Using this, what are the side effects to me in long term.Plz suggest?
A doctor has provided 1 answer
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