A member asked:

Is there a new tx for aca stage 4 nsclc with mets to brain and pelvis depending on tissue sampling match for kras mutation: chem & radia t, stopped.

3 doctors weighed in across 2 answers
Dr. Liawaty Ho answered

Specializes in Hematology and Oncology

Clinical trials: See for trials with mek inhibitor. http://clinicaltrials.gov/ct2/results?term=lung+cancer+k+ras+mutation&pg=3 one of them selumetinib shows a promising result in advanced stage of adenoca with kras mutation. http://www.medscape.com/viewarticle/779075.

Answered 4/21/2013

5.2k views

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Dr. Craig Carter answered

Specializes in Thoracic Surgery

No: Treatment of stage 4 nsclc is chemotherapy/ radiation therapy. Surgery is no an option unless it is for symptom control (bleeding). Immunotherapy, radiofrequency ablation, cryoablation, and other therapies are being tested and utilized, but if the primary therapies are no longer in use, then supportive care should be considered.

Answered 12/16/2014

5.1k views

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