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Ridgeland, MS
A 58-year-old female asked:

Is there a new tx for aca stage 4 nsclc with mets to brain and pelvis depending on tissue sampling match for kras mutation: chem & radia t, stopped.

2 doctor answers3 doctors weighed in
Dr. Liawaty Ho
Hematology and Oncology 23 years experience
Clinical trials: See for trials with mek inhibitor. http://clinicaltrials.gov/ct2/results?term=lung+cancer+k+ras+mutation&pg=3 one of them selumetinib shows a promising result in advanced stage of adenoca with kras mutation. http://www.medscape.com/viewarticle/779075.
Dr. Craig Carter
Thoracic Surgery 40 years experience
No: Treatment of stage 4 nsclc is chemotherapy/ radiation therapy. Surgery is no an option unless it is for symptom control (bleeding). Immunotherapy, radiofrequency ablation, cryoablation, and other therapies are being tested and utilized, but if the primary therapies are no longer in use, then supportive care should be considered.

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Last updated Dec 16, 2014

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