A member asked:

I'm in the process of switching from 100mg a day zoloft to 10mg a day of prozac. i feel prozac helps way better with anxiety. what is the best way to transition from one to another with regards to tapering. thank you for any assistance?

2 doctors weighed in across 2 answers

Prozac takes longer to reach therapeutic levels so if I were you I would start the Prozac and then in two weeks decrease the Zoloft to 50 mg and then in two more weeks stop it.

Answered 7/27/2021

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Dr. TRUC DAO answered

you have a doctor to guide you? Reduce Zoloft in half and start Prozac the same day and stop Zoloft after 2 weeks when Prozac will have started to work

Answered 8/18/2021

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