My husband had the prevnar 13 vaccine . he developed chills and fatigue that evening and some swelling. 2 days later the swelling has gone below the elbow and warm and reddened to touch. uncomfortable. he is seeing his doctor now. does this happen?

Arthus reaction: This is likely an arthus reaction or allergic response to one of many components in the vaccine. Like an insect bite, the local capillaries leak fluid like a soaker hose in a body effort to form a fluid wall around any injected toxin. It would likely fade over several days. It is good to verify this with his doc. It is a good reason not to get the same vaccine again.