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Carson City, NV
A 50-year-old female asked:

Dr ran a protein electrophoresis test on me (both urine and blood). kappa light chains slightly elevated/flagged in serum (21.5) but normal range in urine. no m spike observed and all other values normal. chances of cancer small?

1 doctor answer1 doctor weighed in
Dr. Gurmukh Singh
Pathology 50 years experience
Not a useful test: More than one third of people your age who seek health care have elevated kappa chain levels that are of no consequence other than causing consternation to the patient. If the serum and urine protein electrophoresis were normal, you and your doctor can ignore the kappa chain levels. Wish you good health!
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Last updated Feb 18, 2022

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