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A 34-year-old female asked:

What could be causing high serum iga (700s) if monoclonal protein ruled out with spep, free light chains and immunofixation? normal liver function, normal colonoscopy and negative ana, negative for celiac disease. no known infections present.

1 doctor answer1 doctor weighed in
Dr. Brenainn Flanagan
Family Medicine 14 years experience
Non Specific Finding: Hey so you did all the right things, looking for autoimmune disorders, liver disease and Plasma cell issues. When we see high levels of IGA and all work up is negative we consider it non specific and likely you have had this for many years. Important though is to keep track of it and monitor yourself for symptoms just in case another workup is needed.
Last updated Aug 11, 2020
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