What We Treat
Telehealth
A member asked:
What could be causing high serum iga (700s) if monoclonal protein ruled out with spep, free light chains and immunofixation? normal liver function, normal colonoscopy and negative ana, negative for celiac disease. no known infections present.
A doctor has provided 1 answer
Non Specific Finding: Hey so you did all the right things, looking for autoimmune disorders, liver disease and Plasma cell issues. When we see high levels of IGA and all work up is negative we consider it non specific and likely you have had this for many years. Important though is to keep track of it and monitor yourself for symptoms just in case another workup is needed.
Answered 8/11/2020
54 views
Thank
Related Questions
A member asked:
Gave plasma, leading to tests (cbc, SPEP, immunofixation, FLC). Waiting for hemo consult. Have high IGA (7.09g/l) but low IGG (3.05) &low IGM(.15). Monoclonal IGA type lambda found (8.5mg/l), lambda=33.4mg/l, but LC ratio ok. Am I immune compromised?
2 doctors weighed in across 2 answers
A member asked:
Significance of mildly low IgG(691; 700-1600) & mildly high IgA(400; 90-386)? IgM ok. No monoclonal protein on serum electropho/immunofix & not getting sick more often. Am I immunocompromised? Will rabies vaccine fail? Titer >.5 IU/ml in Oct 2015.
4 doctors weighed in across 2 answers
A member asked:
High albicans, igg, iga, and igm. Serum iron and % sat high, T4 low, and folate (folic acid) low-help where do I start? Have celiac disease.
A doctor has provided 1 answer
A member asked:
High KAPPA/LAMBDA LIGHT CHAIN/slightly high ratio.No Monoclonal protein immunofixation or serum electrophoresis. Is this a type of cancer?Normal WBC
A doctor has provided 1 answer
People also searched for:
High IGA (630) when testing for celiac (neg). Months later sent to hematology with level of 700. k/l ratio, spep, upep, Immunofixation, CBC, CMP, hep panel all normal. Asymmetrical joint pain with negative ANA & RH factor. Colonoscopy 5 yr ago normal
More info on serum immunofixation..no monoclonal proteins detected.a faint IgG labda cannot be ruled out.suggest repeat 6 mths.igg 841 IgA 251 IgM 44.
Slightly elevated beta fraction from serum protein electrophoresis. Beta 1.07 (high) (0.52-0.98) increased beta fraction, no monoclonal or polyclonal gammopathy seen. Immunofixation normal.
Is elevated kappa/lambda ratio on serum FLC test inherently monoclonal, even if neither kappa or lambda is elevated? Ratio high b/c lambda is low, not because of high kappa. SPEP/UPEP & IFE normal. High IgA, low IgG. Clean marrow biopsy. Polyclonal?
Serum free light chain test shows normal kappa (8.7mg/dl), low lambda (3.80), high kap/lam ratio (2.31). Serum $ urine electrophoresis show no monoclonal protein, nor does serum immunofixation. Likely MGUS, myeloma, or admyloidosis? CBC/met panel ok.
Didn't find what you're looking for?
90,000 U.S. doctors in 147 specialties are here to answer your questions or offer you advice, prescriptions, and more.
Ask your questionMore of what we treat
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.
HIPAASecure
SOC 2 Type 2Certified
Get the HealthTap app
Video visit and message your doctor
