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A member asked:
Can letrozole suppress estrogen to where it is undetected and increase fsh to over 60. always ovulate, no hx of spotting until i took femara for iui. doc tested cd 10 (3 days after last dose), said e2 0 and fsh over 60. ?
A doctor has provided 1 answer
Unlikely to be just : femara, more likely perimenopause, premature menopause. Femara suppresses conversion of androgens to estrone, not a direct estrogen suppressor. Should allow normal FSH/estrogen process to allow ovulation to proceed. The androgen/estrone suppresses ovulation while it is present, typically from polycystic ovarian syndrome.
Answered 2/24/2020
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