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A member asked:
Are all acute transformations rare or is there good evidence that the probability of such an occurrence depends upon the particular type of underlying myeloproliferative disorder that a person has? i'm told that there is more than one type of md.
A doctor has provided 1 answer
Depends: On the type of myeloproliferative disorder, highest transformation risk being seen in CML, up to 90% in some studies for refractory cases and as low as 10 % in polycythemia Vera or 5% in essential thrombocythemia.
Answered 1/23/2020
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Related Questions
A member asked:
Are there any treatments for acute transformation of overlap myelodysplascity/myeloproliferative disorder in an elderly patient If so, what are they?
A doctor has provided 1 answer
A member asked:
The question is not about me I understand that an acute transformation of overlap myeloproliferative/myelodyplastictiy disorder is the terminal phase of the disorder But what is a blastic transformation of the disorder? Is it the same thing as an ac?
5 doctors weighed in across 2 answers
A member asked:
Is overlap myelodysplasticity myeloproliferative disorder a name for one disorder with common features of two disorders or the one blood disorder ?
3 doctors weighed in across 2 answers
People also searched for:
A family member has a myeloproliferative disorder. He does have a good hematologist and is stable. However, generally speaking, can an acute transformation take place over a few months, a few weeks or even a few days? We need to be prepared?
A relative has an overlap myeloproliferative/myelodysplastic disorder. He has been told that if it changes into an acute transformation then it may be life-threatening. However, is there some other possible change that could ALSO be life-threatening?
I would appreciate some clarity on an important matter. Are myelodsyplastic and myeloproliferative disorders pre-malignant conditions or are they malignancies by their very nature even before an acute transformation has occurred?
Infection makes it harder to recover from an acute transformation of a myeloproliferative disorder But can the antibiotics also have an adverse effect?
In general, if a 91 yr-old has acute transformation of a myeloproliferative disorder then is it worthwhile to treat the pt, if there is a treatment?
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