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A family member has a myeloproliferative disorder. He does have a good hematologist and is stable. However, generally speaking, can an acute transformation take place over a few months, a few weeks or even a few days? We need to be prepared?
A relative has an overlap myeloproliferative/myelodysplastic disorder. He has been told that if it changes into an acute transformation then it may be life-threatening. However, is there some other possible change that could ALSO be life-threatening?
I would appreciate some clarity on an important matter. Are myelodsyplastic and myeloproliferative disorders pre-malignant conditions or are they malignancies by their very nature even before an acute transformation has occurred?
Infection makes it harder to recover from an acute transformation of a myeloproliferative disorder But can the antibiotics also have an adverse effect?
In general, if a 91 yr-old has acute transformation of a myeloproliferative disorder then is it worthwhile to treat the pt, if there is a treatment?
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