A 23-year-old female asked:
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colon polyp removed from me was deemed to be elastofibroma but mayo clinic wants to run one more test, congo red stain, to rule out possibility of amyloidosis deposites. can the two be mistaken for each other?

1 doctor answer
Dr. Shaban Faruqui
Specializes in Gastroenterology
Polyp (EF) neg. CR S: Elastofibromatous change in Colon is rare, *Elastosis - increase in Elastic fibres in submucosa.Called *elastofibroma if forms a polyp, commoinly affects Left colon, age usually > 45 yrs.May be asymptomatic or NSpec. GI symptoms Elastin stain highlights elastic fibres On m/e -Grey amorphous material, occ. Fibrous tissue, inv. submocusa & MM.,mimics Amyloidosis - Congo Red Stain +ve (-ve in EF)
Answered on Aug 17, 2019
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