A member asked:

I had a monospot test one year ago and was positive for mono. now 11 months later i've had anotherpositive. could this be the same infection?

2 doctors weighed in across 2 answers

Same antibodies: The simple screening test for mono often just indicates the presence of antibodies to the EB virus which should be present for quite a while. Viral detection studies could be ordered but these are more expensive & generally reserved for confusing cases. Specific IgM antibody to the EB virus is more specific to new infection but this fades leaving the IgG antibody for long term

Answered 5/7/2017

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Monospot: Monospot can remain positive up to a year after initial mono infection.

Answered 5/7/2017

705 views

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