A 31-year-old male asked:
Possible to have an autoimmune disease w/ very low c-reactive protein & esr/sed rate? ana is negative, but doc said he thinks i have something autoimmune going on. i always thought autoimmune diseases were inherently inflammatory in nature?
2 doctor answers • 2 doctors weighed in
Internal Medicine 59 years experience
794 viewsAnswered >2 years ago
Rheumatology 33 years experience
Yes and No: You are correct that we lump autoimmune and inflammation together. The problem with autoimmune labs is they can change almost day to day. There are certainly more tests then an ANA that can be positive even in light of a negative ANA. A good history and physical exam are more important then labs even though labs and xrays can be helpful and supportive of a diagnosis. Your doctor may be correct
793 viewsAnswered >2 years ago
Last updated Feb 19, 2017
Connect with a U.S. board-certified doctor by text or video anytime, anywhere.
24/7 visits - just $39!
50% off with $15/month membership
Content on HealthTap (including answers) should not be used for medical advice, diagnosis, or treatment, and interactions on HealthTap do not create a doctor-patient relationship. Never disregard or delay professional medical advice in person because of anything on HealthTap. Call your doctor or 911 if you think you may have a medical emergency.