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Swartz Creek, MI
A 55-year-old female asked:

Esr is elevated but my ana and crp are normal! does this mean that i don't have an autoimmune disease?

2 doctor answers6 doctors weighed in
Dr. Martin Raff
Infectious Disease 57 years experience
No: Lab data removed from the clinical picture have little meaning. A negative test has relatively little relevance. The ESR is a non-specific measure of intravascular inflammation, as is the CRP but for differing reasons. You should discuss this with your treating doctor, or ask for a rheumatology consultation. Good luck.
Dr. Ramachandran Srinivasan
Rheumatology 53 years experience
Autoimmune disorders: Esr is an inflammatory marker tha is elevated in inflammatory disorders, anemia , pregnancy, , kidney cancers , tb, lymphoma to name a few. It measures rate at which red cells sediment in a test tube in 1 hour. It is used more to monitor response to treatmemt is such disorders and helps in diagnosis of certain conditions. Esr can be elevated with negative ANA in several autoimmune disorders.

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Last updated Sep 20, 2018

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