My lab results show low white blood cell count & liver enzymes over 1000. found out i have enlarged spleen and cholecystitis. what could be the cause?

Liver disease: Cholesystitis doesn't usually cause a low white count, enlarged spleen and severe elevation of liver enzymes. Chronic hepatitis is suggested. It could be viral or autoimmune. A gastroenterologist should be involved in your care, and an abdominal surgeon should be consulted about the inflammation of the gall bladder which may be chronic rather than acute.