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A 39-year-old female asked:

If child has nf1 and parents are negative, but were told it could be in reproductive cells, is it possible for 2nd child to not have it, but 3rd does?

1 doctor answer5 doctors weighed in
Dr. Robert Kwok
Pediatrics 34 years experience
New mutation?: If neither parent carries a mutation for NF (neurofibromatosis), then the affected child is a new mutation. Each future child has a very rare risk of having a separate new mutation causing NF. Realize that every child in the world has a rare chance of getting a new mutation causing NF. No worries... unless one's geneticist feels there is a reason to worry. If so, the geneticist can evaluate more.
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Last updated Nov 28, 2017

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